woman getting mesotherapy at medical spa

What should you know about mesotherapy side effects before diving into this popular treatment? This concise guide covers the spectrum of potential reactions, from the common to the rare, ensuring you’re well-informed. We’ll discuss what to expect, how to mitigate risks, and when to seek medical advice, providing a clear pathway to making a safe and informed decision about mesotherapy.

Key Takeaways

  • Mesotherapy is a minimally invasive procedure that injects a cocktail of substances into the skin to address various medical and cosmetic issues, but carries potential side effects such as nausea, skin reactions, and allergic responses which should be assessed by a healthcare professional.
  • Proper pre-treatment care, including disclosing medical history and avoiding certain medications, and post-treatment care, like refraining from physical activities and avoiding contact with the treated area, are crucial for minimizing side effects and ensuring a successful outcome.
  • The effectiveness and safety of mesotherapy can be significantly influenced by the practitioner’s experience and qualification, as well as the treatment’s compatibility with the patient’s health status, indicating the importance of thorough medical consultation and consideration of contraindications.

Mesotherapy: A Brief Overview

Mesotherapy is a unique medical procedure developed by Dr. Michel Pistor in 1952, and it has been recognized as a medical specialty by The French National Academy of Medicine since 1987. The mesotherapy procedure involves the use of fine needles to inject a compound mixture intradermally or subcutaneously, a technique that can be applied in various methods such as point by point, Nappage, or epidermic methods. Mesotherapy injections have gained broad acceptance for various medical and cosmetic issues like pain management, biorejuvenation, alopecia, skin rejuvenation, fat removal, and body contouring.

In a typical mesotherapy session, substances like minerals, vitamins, amino acids, hyaluronic acid, antioxidants, and other medications are tailored to the patient’s condition and injected to improve blood circulation and stimulate the desired outcomes. What makes this medical procedure stand out is its cost-effectiveness, minimal invasive nature, and quicker benefits, such as optimized skin improvement results after multiple sessions.

Types of Mesotherapy

Mesotherapy involves several types of treatments, including:

  • Point by point mesotherapy: In this method, a specific amount of drug solution is injected perpendicular to the skin at a depth of 4 mm, with the injections spaced 1 cm to 2 cm apart. This precision ensures that the desired area receives an adequate amount of the injected substances for optimal results.
  • Upper skin mesotherapy
  • Comprehensive mesotherapy

On the other hand, there are different techniques for administering injections in mesotherapy:

  1. The Point by Point technique involves injecting directly into the target area.
  2. The Nappage technique involves superficial injections over a large surface area, given at a 45-degree angle while flicking the wrist rapidly.
  3. The upper skin mesotherapy technique involves injections at a shallow depth of 1 mm into the skin.

Each of these techniques has its unique characteristics and can be chosen based on the patient’s condition and desired outcomes.

Common Side Effects of Mesotherapy

As with any medical procedure, mesotherapy carries its own set of side effects. Awareness of potential risks is key before embarking on this treatment. Common side effects may involve:

  • Nausea
  • Vomiting
  • Diarrhea
  • Mild pain
  • Skin hyperesthesia
  • Edema
  • Itching
  • Erythema
  • Tender subcutaneous nodules at the injection site

It is important to consult with a healthcare professional before undergoing mesotherapy to fully understand the potential side effects and risks involved.

Moreover, allergic reactions are also common side effects of mesotherapy and can be mitigated through proper monitoring. It’s important to remember that while these side effects may sound alarming, with proper care and precaution, they are manageable and often temporary. We’ll now explore these side effects in more detail along with effective management strategies.

Skin Reactions

Skin reactions are among the most common side effects of mesotherapy. These include redness, swelling, and bruising post-treatment. While these reactions are usually temporary, they can cause discomfort and might affect your daily activities.

To reduce redness and swelling after the procedure, patients can apply a cool compress to the treated area and take over-the-counter pain relievers. Individuals prone to bruising or with sensitive skin may experience more bruising post-mesotherapy. However, this risk can be lessened by avoiding blood-thinning medications before the treatment.

Lastly, patients are advised to use a gentle moisturizer and avoid harsh skincare products to alleviate any dryness and flaking of the skin after mesotherapy.

Allergic Reactions

Allergic reactions are another common side effect associated with mesotherapy. These hypersensitivity reactions could be immediate or delayed, with symptoms including a maculopapular rash distant from the treated area.

Preventing allergic reactions involves careful planning and disclosure. Prior to receiving treatment, disclosing any known allergies to the healthcare provider can significantly reduce the risk of allergic reactions to mesotherapy. Individuals with a known allergy to any of the compounds used in the microinjection for mesotherapy are contraindicated from receiving the therapy. It is also important to remember that allergic reactions during mesotherapy can be triggered by certain medications used in the procedure. Some steps to prevent allergic reactions during mesotherapy include:

  • Disclosing any known allergies to the healthcare provider
  • Avoiding mesotherapy if you have a known allergy to any of the compounds used
  • Being aware of the medications used in the procedure and discussing any potential allergies with your healthcare provider

By taking these precautions, you can help reduce the risk of allergic reactions during mesotherapy.

Minimizing Discomfort and Risks

Although the side effects of mesotherapy might seem intimidating, several strategies can effectively minimize discomfort and risks. Selecting a qualified and experienced provider is one of the most effective strategies. This ensures that the procedure is carried out professionally and reduces the risk of complications such as infection, allergic reactions, and scarring.

Adhering to pre- and post-treatment care instructions also plays a crucial role in minimizing discomfort and risks associated with this procedure. It is essential to report any significant pain or discomfort during or after mesotherapy to the provider immediately.

Next, we’ll examine the pre- and post-treatment care instructions in more detail.

Pre-Treatment Care

Before you undergo mesotherapy, there are some necessary pre-treatment care steps that you should follow. First and foremost, patients should disclose their full medical history, including any allergies, to avoid adverse reactions. Informing the practitioner about any medications you are currently taking is also crucial, as some medications may interact with the substances used in mesotherapy.

Before undergoing the procedure, there are several precautions and preparations that patients should take into consideration:

  • Do not take anticoagulant medication without medical consent, as it could increase the risk of bruising.
  • Avoid consuming alcohol and taking anti-inflammatory drugs for at least one week before treatment to minimize bruising.
  • Ensure that the treatment area is healthy, without any skin infections or inflammation.

These careful preparations can help ensure a smooth procedure and recovery.

Post-Treatment Care

Post-treatment care is equally important as pre-treatment care in ensuring a successful outcome and speedy recovery. Adherence to the aftercare instructions provided by the healthcare provider is critical. These instructions typically include:

  • Avoiding blood-thinning medications
  • Keeping the treated area away from water for 10-15 hours
  • Refraining from physical force or exercise for two days
  • Avoiding makeup for 10-15 hours
  • Preventing any contact with the treated area

Patients are also advised to consult with their healthcare provider for any concerns post-treatment and to schedule an individual appointment with a beautician for specific post-treatment care inquiries.

Contraindications and Unsuitable Candidates

Despite its diverse applications, mesotherapy is not a suitable treatment for everyone. It is contraindicated for individuals with:

  • a body mass index (BMI) over 30
  • hypersensitivity to the injection components
  • those under 18 years of age
  • pregnant or lactating women
  • people with certain medical conditions or specific diseases.

There are also adverse effects such as anxiety, tremor, palpitations, and muscle cramps due to potassium wasting that may occur following mesotherapy, signaling potential allergic reactions to certain components. Furthermore, individuals with histories of paralysis, diabetes requiring insulin management, active cancer, blood coagulation disorders, or urticaria/hives should avoid mesotherapy. Patients with cardiac diseases on multiple medications are also advised against it. It’s crucial to discuss your medical history in detail with your healthcare provider before deciding on this treatment.

Combining Mesotherapy with Other Treatments

If you’re aiming for enhanced aesthetic improvement, you might consider pairing mesotherapy with other cosmetic procedures. Mesotherapy can be complemented with:

Such combinations allow for the simultaneous targeting of facial rejuvenation concerns, including:

  • deep wrinkles
  • larger fat deposits, including excess fat and fat cells
  • dynamic wrinkles
  • skin surface irregularities
  • age spots or de-pigmentation

While combining treatments can provide enhanced results, it is crucial to assess how these combinations may affect the side effects experienced from mesotherapy. Consulting with a qualified practitioner will help you make an informed decision about the best combination of treatments for your specific needs.

Needle-Free Mesotherapy: An Alternative Option

For those who dread the thought of needles, there is an alternative option – needle-free mesotherapy. This non-invasive alternative uses ultrasonic technology instead of injections, making it a pain-free option suitable for all skin types.

The ultrasonic technology employed in needle-free mesotherapy significantly boosts the skin’s absorption of nutrients into the middle layer, allowing for an absorption rate up to 2,000 times greater than traditional methods using very fine needles. This needle-free approach can be used as an adjunct to traditional mesotherapy sessions or as an exclusive treatment method, offering frequent benefits without invasive techniques.

Products like SMARTMeso utilize advanced technologies such as fractional mesotherapy and electroporation to effectively deliver serums into the skin without the need for needles.

Importance of Choosing a Qualified Practitioner

Selecting a qualified practitioner is a vital step when you’re considering mesotherapy. This ensures that the procedure is carried out professionally and reduces the risk of complications such as infection, allergic reactions, and scarring.

A reliable practitioner should have:

  • undertaken specific training in mesotherapy techniques for assured skillfulness
  • be someone you trust and who provides comprehensive answers to your questions, enhancing your comfort and security during the treatment
  • be able to provide before and after images from previous mesotherapy treatments for evaluation of the quality and success

Beyond seeking low prices, considering the practitioner’s certification and authorization is essential when evaluating mesotherapy costs, as these factors ensure your safety and well-being.

Mesotherapy Costs and Factors Affecting Prices

The cost of mesotherapy is influenced by several factors, including:

  • Geographic location: Higher costs are typically found in major metropolitan areas and coastal regions, reflecting local living and operational costs.
  • Reputable clinics: They often have higher mesotherapy treatment costs due to their recognized quality of service and experienced physicians.
  • Type of mesotherapy treatment: Different treatments may have different costs.
  • Grade of ingredients used: Higher quality ingredients may result in higher costs.
  • Area being treated: Larger areas may require more product and therefore have higher costs.
  • Required number of sessions: Multiple sessions may be needed for optimal results, which can increase the overall cost.

It’s important to remember that cosmetic mesotherapy treatments are generally more expensive than therapeutic ones due to the absence of insurance coverage for cosmetic procedures. However, investing in a mesotherapy treatment at a reputable clinic can be crucial for receiving high-quality care and minimizing risks.


In a world where aesthetic enhancement and pain management options abound, mesotherapy stands out as a minimally invasive, cost-effective procedure with faster benefits. From its inception in 1952 by Dr. Michel Pistor, it has served a variety of medical and cosmetic purposes offering optimized results after multiple sessions. However, like any medical procedure, it comes with its set of side effects such as skin reactions and allergic reactions, which can be effectively managed with proper care and precautions.

Choosing a qualified practitioner and following pre- and post-treatment care instructions are vital in minimizing discomfort and potential risks. Moreover, understanding contraindications and assessing your suitability for the treatment is crucial. For enhanced aesthetic improvement, mesotherapy can be combined with other cosmetic procedures under the guidance of a qualified practitioner. And for those who dread needles, needle-free mesotherapy provides a pain-free alternative.

As we conclude, remember that understanding the procedure, potential side effects, and how to manage them is the first step towards a safe and successful mesotherapy journey. With the right practitioner, proper care, and adherence to guidelines, you can enjoy the benefits of mesotherapy while minimizing potential risks.

Frequently Asked Questions

What is mesotherapy used for?

Mesotherapy is used for a range of medical and cosmetic purposes, including pain management, biorejuvenation, alopecia treatment, skin rejuvenation, and fat removal.

What are the common side effects of mesotherapy?

The common side effects of mesotherapy may include nausea, vomiting, diarrhea, mild pain, skin hyperesthesia, edema, itching, erythema, and tender subcutaneous nodules at the injection site. It’s important to be aware of these potential effects before considering the treatment.

Who should avoid mesotherapy?

Mesotherapy should be avoided by individuals with a body mass index over 30, hypersensitivity to the injection components, those under 18 years of age, pregnant or lactating women, and people with certain medical conditions or specific diseases. It’s important to consider these factors before considering mesotherapy.

Can mesotherapy be combined with other treatments?

Yes, mesotherapy can be combined with other cosmetic procedures to enhance its effects on aesthetic improvement.

How much does mesotherapy cost?

Mesotherapy costs vary based on factors such as clinic location, reputation, treatment type, ingredients used, and required sessions.

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